Antiplatelet Therapy and Platelet Function Testing

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Ekaterina Lenk, Michael Spannagl Platelet Function Testing-guided Antiplatelet Therapy Platelet Function Testing-guided Antiplatelet Therapy

Cardiovascular diseases are the leading cause of death in the Western world. Several factors have led to the increase in vascular disorders, including the aging population, unhealthy lifestyles, increasing rates of diabetes and raised lipids, and further risk factors resulting in inflammation and calcification of the vascular endothelium. Activated platelets in damaged blood vessels can trigger...

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Antiplatelet therapy and platelet function testing.

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Platelet Function Testing-Guided Antiplatelet Therapy

Cardiovascular diseases are the leading cause of death in the Western world. Several factors have led to the increase in vascular disorders, including the aging population, unhealthy lifestyles, increasing rates of diabetes and raised lipids, and further risk factors resulting in inflammation and calcification of the vascular endothelium. Activated platelets in damaged blood vessels can trigger...

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Platelet function tests and resistance to antiplatelet therapy.

The clinical efficacy of antiplatelet therapy (aspirin, P2Y12 and glycoprotein IIb/IIIa receptor antagonists) to prevent occlusive arterial events in patients with atherothrombotic disease is well established. Despite the proven benefits of antiplatelet therapy, many patients continue to experience arterial events. Many factors may influence the response of platelets to antiplatelet therapy and...

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Platelet function testing to time surgery in patients on dual antiplatelet therapy?

In patients pretreated with P2Y12 receptor inhibitors who need to undergo non-emergent cardiac or major non-cardiac surgery, current guidelines of the European Society of Cardiology recommend postponing surgery for at least five days after last intake of clopidogrel or ticagrelor, and for seven days after last intake of prasugrel, unless there is high risk of ischemic events. However, a fixed f...

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ژورنال

عنوان ژورنال: Clinical Cardiology

سال: 2008

ISSN: 0160-9289,1932-8737

DOI: 10.1002/clc.20371